Taurine is a natural occurring amino acid in the body that declines with age and stress. IV L-taurine has been studied for its potential benefits in various physiological processes in the body. Some of these benefits may indirectly contribute to the management of migraines. It is commonly used to support better physical function, mitigate cardiovascular risks after exercising, improve issues associated with heart failure, reduce inflammation, and lower blood pressure. According to research done at Intellectual Medicine University, the recommended dose for IV L-Taurine is 200-2000 mg, with the average dose being 250-500 mg to see benefits (Petteruti, 2023).
Here are a few benefits of L-taurine that could be relevant to migraines:
1. Neurotransmitter modulation: L-taurine has been shown to regulate the release of neurotransmitters such as serotonin and dopamine, which are involved in pain modulation. Imbalances in these neurotransmitters can contribute to migraines. By modulating neurotransmitters, L-taurine helps reduce the intensity and duration of migraine attacks.
2. Antioxidant properties: L-taurine has antioxidant properties, meaning it can help neutralize harmful free radicals in the body. Oxidative stress, which occurs when there is an imbalance between free radicals and antioxidants, has been implicated in migraine pathophysiology. By reducing oxidative stress, L-taurine may help alleviate migraine symptoms and prevent their occurrence.
3. Anti-inflammatory effects: Inflammation is believed to play a role in migraines, and reducing inflammation may help alleviate symptoms. L-taurine has been shown to inhibit the production of pro-inflammatory molecules, suggesting it may have a protective effect against migraines.
While these potential benefits of L-taurine are promising, it is important to note that the research on IV L-taurine specifically for migraines is limited. More studies are needed to establish its efficacy and optimal dosage for this specific condition.
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References:
Barbosa J, et al. Taurine: A Potential Ergogenic Aid for Preventing Muscle Damage and Protein Catabolism and Decreasing Oxidative Stress Produced by Endurance Exercise. Frontiers in Physiology. 2018; 9: 756. doi: 10.3389/fphys.2018.00756.
Geary GG, et al. Taurine Supplementation Alleviates Delayed Brain Injury After Subarachnoid Hemorrhage in Rats. Amino Acids. 2018; 50(6): 697-706. doi: 10.1007/s00726-018-2562-7.
Ghanizadeh A, et al. Taurine as an Add-on Treatment in Children and Adolescents with Bipolar Disorders: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of Child and Adolescent Psychopharmacology. 2016; 26(9): 784-791. doi: 10.1089/cap.2016.0062.
Hansen SH, et al. Taurine and Taurine Deficiency in the Cat. Journal of Animal Physiology and Animal Nutrition. 2006; 90(1-2): 53-62. doi: 10.1111/j.1439-0396.2005.00595.x.
Kim HY, et al. Taurine in Drinking Water Recovers Learning and Memory in the Adult APP/PS1 Mouse Model of Alzheimer’s Disease. Scientific Reports. 2014; 4: 7467. doi: 10.1038/srep07467.
Petteruti, S. L-Taurine Drug Reference Card. IV Therapy Course. Intellectual Medicine University. 2023.
Xu YJ, et al. Taurine Supplementation Reduces Neurological Deficits and Neuronal Damage After Transient Global Cerebral Ischemia in Rats. Advances in Experimental Medicine and Biology. 2017; 975(Pt 2): 1045-1057. doi: 10.1007/978-94-024-1079-2_84.
